Biotin-PEG4-methyltetrazine
Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
Product Specifications
CAS Number
1835759-81-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.18
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NCCOCCOCCOCCOC1=CC=C(C2=NN=C(C)N=N2)C=C1)CCCC[C@H]3SC[C@@]([C@@]3([H])N4)([H])NC4=O
Molecular Formula
C27H39N7O6S
Molecular Weight
589.71
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RK12411 96 Tests
Human Vasoactive intestinal polypeptide receptor 2 (VIPR2) ELISA Kit
Sign In for Pricing
View Details 