(±) 11 (12) -EET methyl ester
(±) 11 (12) -EET methyl ester (11,12-EET-methyl ester) is a methylated derivative of 11,12-epoxyeicosatrienoic acid (11,12-EET) (HY-130494) . (±) 11 (12) -EET methyl ester cannot induce β-arrestin recruitment of the G protein-coupled receptor GPR132. (±) 11 (12) -EET methyl ester fails to enhance the expression of hematopoietic stem and progenitor cell (HSPC) markers. (±) 11 (12) -EET methyl ester can be used as a negative control molecule to study the structure-function relationship of 11,12-EET, facilitating the analysis of the role of the oxygenated fatty acid-GPR132 signaling axis in hematopoiesis[1].
Product Specifications
CAS Number
[90693-45-1]
Product Name Alternative
11,12-EET methyl ester; (±) 11,12-EpETrE methyl ester
UNSPSC
12352211
Target
Drug Derivative
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Smiles
CCCCC/C=C\C[C@@H]1[C@H](C/C=C\C/C=C\CCCC(OC)=O)O1
Molecular Formula
C21H34O3
Molecular Weight
334.49
References & Citations
[1]Lahvic JL, et al. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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