AT-56 (Standard)
AT-56 (Standard) is the analytical standard of AT-56. This product is intended for research and analytical applications. AT-56 is a potent, selective and orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS), with an IC50 of 95 μM and Ki of 75 μM. AT-56 could selectively suppress the drowsiness or pain reaction mediated by L-PGDS-catalyzed PGD2[1].
Product Specifications
CAS Number
162640-98-4
UNSPSC
12352100
Hazard Statement
H228, H315, H319
Target
PGE synthase; Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology
Purity
98.41
Smiles
N1(CCCCC2=NNN=N2)CC/C(CC1)=C3C4=CC=CC=C4C=CC5=CC=CC=C/35
Molecular Formula
C25H27N5
Molecular Weight
397.52
Precautions
H228, H315, H319
References & Citations
[1]Irikura D, et, al. Biochemical, functional, and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin D synthase. J Biol Chem. 2009 Mar 20; 284 (12) : 7623-30.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS9422632-01 0.02 mg
Recombinant Calloselasma rhodostoma Thrombin-like enzyme ancrod
Sign In for Pricing
View Details MBS9422632-02 0.1 mg
Recombinant Calloselasma rhodostoma Thrombin-like enzyme ancrod
Sign In for Pricing
View Details