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AT-56 (Standard)

AT-56 (Standard) is the analytical standard of AT-56. This product is intended for research and analytical applications. AT-56 is a potent, selective and orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS), with an IC50 of 95 μM and Ki of 75 μM. AT-56 could selectively suppress the drowsiness or pain reaction mediated by L-PGDS-catalyzed PGD2[1].

Product Specifications

CAS Number

[162640-98-4]

UNSPSC

12352100

Hazard Statement

H228, H315, H319

Target

PGE synthase; Reference Standards

Related Pathways

Immunology/Inflammation; Others

Field of Research

Inflammation/Immunology

Purity

98.41

Smiles

N1(CCCCC2=NNN=N2)CC/C(CC1)=C3C4=CC=CC=C4C=CC5=CC=CC=C/35

Molecular Formula

C25H27N5

Molecular Weight

397.52

Precautions

H228, H315, H319

References & Citations

[1]Irikura D, et, al. Biochemical, functional, and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin D synthase. J Biol Chem. 2009 Mar 20; 284 (12) : 7623-30.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, sealed storage, away from light and moisture

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-13988R/AT-56-Standard-SDS-MedChemExpress.pdf

Scientific Category

Reference Standards

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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