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UNC0642 (Standard)

UNC0642 (Standard) is the analytical standard of UNC0642. This product is intended for research and analytical applications. UNC0642 is a potent and selective lysine methyltransferases G9a and GLP inhibitor, with an IC50 of <2.5 nM for G9a.

Product Specifications

CAS Number

1481677-78-4

UNSPSC

12352100

Target

Histone Methyltransferase; Reference Standards

Related Pathways

Epigenetics; Others

Field of Research

Cancer

Smiles

CC(N1CCC(NC2=C3C=C(OC)C(OCCCN4CCCC4)=CC3=NC(N5CCC(F)(F)CC5)=N2)CC1)C

Molecular Formula

C29H44F2N6O2

Molecular Weight

546.70

References & Citations

[1]Liu F, et al. Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP. J Med Chem. 2013 Nov 14;56 (21) :8931-8942.|[2]Wang L, et al. Targeting EHMT2 reverses EGFR-TKI resistance in NSCLC by epigenetically regulating the PTEN/AKT signaling pathway. Cell Death Dis. 2018 Jan 26;9 (2) :129

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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