ZCL278-13C

ZCL278-13C is 13C-labeled ZCL278 (HY-13963) . ZCL278 is a selective Cdc42 modulator that directly binds to Cdc42 and inhibits its functions with Kd of 11.4 μM for Cdc42-ZCL278 affinity in surface plasmon resonance (SPR) experiment.

Product Specifications

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer; Infection

Smiles

S=C(NC1=CC=C(C=C1)S(=O)(NC2=NC(C)=CC(C)=N2)=O)N[13C](COC3=CC=C(C=C3Cl)Br)=O

Molecular Formula

C20 13CH19BrClN5O4S2

Molecular Weight

585.89

References & Citations

[1]Friesland A, et al. Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility. Proc Natl Acad Sci U S A. 2013 Jan 22;110 (4) :1261-6.