2-Deoxy-D-glucose 6-phosphate (sodium)

2-Deoxy-D-glucose 6-phosphate sodium, a derivative of 2-Deoxy-D-glucose (HY-13966), is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].

Product Specifications

UNSPSC

12352211

Target

Drug Derivative

Related Pathways

Others

Field of Research

Metabolic Disease

Smiles

O=CC[C@H]([C@@H]([C@@H](COP(O)(O[Na])=O)O)O)O

Molecular Formula

C6H12NaO8P

Molecular Weight

266.12

References & Citations

[1]Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65 (15) :7023-30.|[2]B Pajak, et al. 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents. Int J Mol Sci. 2019 Dec 29;21 (1) :234.