Hydroxyfasudil (Standard)
Hydroxyfasudil (Standard) is the analytical standard of Hydroxyfasudil. This product is intended for research and analytical applications. Hydroxyfasudil is a ROCK inhibitor, with IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively.
Product Specifications
UNSPSC
12352100
Target
Reference Standards; ROCK
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Others; Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Smiles
O=C1NC=CC2=C1C=CC=C2S(=O)(N3CCNCCC3)=O
Molecular Formula
C14H17N3O3S
Molecular Weight
307.38
References & Citations
[1]Rikitake Y, et al. Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection. Stroke. 2005 Oct;36 (10) :2251-7. Epub 2005 Sep 1.|[2]Masago T, et al. Effect of the rho-kinase inhibitor hydroxyfasudil on bladder overactivity: an experimental rat model. Int J Urol. 2009 Oct;16 (10) :842-7.|[3]Saito M, et al. Hydroxyfasudil ameliorates penile dysfunction in the male spontaneously hypertensive rat. Pharmacol Res. 2012 Oct;66 (4) :325-31.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13911R/
Scientific Category
Reference Standards
CAS Number
[105628-72-6]
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