Hydroxyfasudil (Standard)

Hydroxyfasudil (Standard) is the analytical standard of Hydroxyfasudil. This product is intended for research and analytical applications. Hydroxyfasudil is a ROCK inhibitor, with IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively.

Product Specifications

CAS Number

[105628-72-6]

UNSPSC

12352100

Target

Reference Standards; ROCK

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Others; Stem Cell/Wnt; TGF-beta/Smad

Field of Research

Cancer; Inflammation/Immunology; Cardiovascular Disease

Smiles

O=C1NC=CC2=C1C=CC=C2S(=O)(N3CCNCCC3)=O

Molecular Formula

C14H17N3O3S

Molecular Weight

307.38

References & Citations

[1]Rikitake Y, et al. Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection. Stroke. 2005 Oct;36 (10) :2251-7. Epub 2005 Sep 1.|[2]Masago T, et al. Effect of the rho-kinase inhibitor hydroxyfasudil on bladder overactivity: an experimental rat model. Int J Urol. 2009 Oct;16 (10) :842-7.|[3]Saito M, et al. Hydroxyfasudil ameliorates penile dysfunction in the male spontaneously hypertensive rat. Pharmacol Res. 2012 Oct;66 (4) :325-31.