25 (S) -27-Hydroxy cholesterol

25 (S) -27-Hydroxy cholesterol is a metabolite of CYP27A1 mediated cholesterol hydroxylation. 25 (S) -27-Hydroxy cholesterol inhibits melanoma cell proliferation[1].

Product Specifications

CAS Number

[56845-83-1]

UNSPSC

12352211

Target

LXR

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC[C@H](C)CO)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C

Molecular Formula

C27H46O2

Molecular Weight

402.65

References & Citations

[1]Tuckey RC, et al. CYP27A1 acts on the pre-vitamin D3 photoproduct, lumisterol, producing biologically active hydroxy-metabolites. J Steroid Biochem Mol Biol. 2018 Jul;181:1-10.