NXN-188
NXN-188 is a combined nNOS inhibitor and an agonist of 5HT-1B/1D receptor. NXN-188 can be studied in research on migraine[1].
Product Specifications
CAS Number
[915036-97-4]
UNSPSC
12352005
Target
5-HT Receptor; NO Synthase
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
N=C(C1=CC=CS1)NC2=CC3=C(NC=C3C4=CCN(C)CC4)C=C2
Molecular Formula
C19H20N4S
Molecular Weight
336.45
References & Citations
[1]Hougaard, A., et al., (2013) . The nitric oxide synthase inhibitor and serotonin-receptor agonist NXN-188 during the aura phase of migraine with aura: A randomized, double-blind, placebo-controlled cross-over study. Scandinavian journal of pain, 4 (1), 48-52.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Curated Selection
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