2- (Tetradecylthio) acetic acid

2-Tetradecylthio acetic acid is a pan-peroxisome proliferator activated receptor (pan-PPAR) activator. 2-Tetradecylthio acetic acid induces hypolipidemia. 2-Tetradecylthio acetic acid reduces plasma lipids and enhances hepatic fatty acid oxidation in rodents. 2-Tetradecylthio acetic acid increases the expression of genes involved in fatty acid uptake, activation, accumulation, and oxidation[1][2].

Product Specifications

CAS Number

[2921-20-2]

Product Name Alternative

Tetradecylthioacetic acid

UNSPSC

12352211

Hazard Statement

H315, H319

Target

PPAR

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Purity

99.81

Solubility

DMSO : ≥ 2 mg/mL

Smiles

O=C(O)CSCCCCCCCCCCCCCC

Molecular Formula

C16H32O2S

Molecular Weight

288.49

Precautions

H315, H319

References & Citations

[1]Vaagenes H, et al. Methylated eicosapentaenoic acid and tetradecylthioacetic acid: effects on fatty acid metabolism. Biochem Pharmacol. 1999 Oct 1;58 (7) :1133-43.