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CRHR1 antagonist 1

CRHR1 antagonist 1 (compound 10a) is a non-peptide corticotropin-releasing hormone type 1 receptor (CRHR1) antagonist. CRHR1 antagonist 1 can be utilized in mental disorders research[1].

Product Specifications

CAS Number

[276890-57-4]

UNSPSC

12352005

Target

CRFR

Related Pathways

GPCR/G Protein

Field of Research

Neurological Disease

Smiles

OCCCCN(CC)C1=C2C(N(C3=C(C)C=C(C)C=C3C)C(C)=C2C)=NC(C)=N1

Molecular Formula

C24H34N4O

Molecular Weight

394.55

References & Citations

[1]Hsin LW, et al. Synthesis and biological activity of fluoro-substituted pyrrolo[2,3-d]pyrimidines: the development of potential positron emission tomography imaging agents for the corticotropin-releasing hormone type 1 receptor. Bioorg Med Chem Lett. 2000 Apr 17;10 (8) :707-10.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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