Tetraacetylphytosphingosine
Tetraacetylphytosphingosine is a sphingolipid metabolite produced by phytosphingosine acetylation. Tetraacetylphytosphingosine exerts its inhibitory action on angiogenesis through the inhibition of MAPK activation and intracellular calcium increase[1]. Tetraacetylphytosphingosine induces apoptosis in HaCaT cells[2].
Product Specifications
CAS Number
13018-48-9
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; p38 MAPK
Related Pathways
Apoptosis; MAPK/ERK Pathway
Field of Research
Cancer; Cardiovascular Disease
Purity
99.90
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCC[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](NC(C)=O)COC(C)=O
Molecular Formula
C26H47NO7
Molecular Weight
485.65
Precautions
H302, H315, H319, H335
References & Citations
[1]Yoo Bin Kwon, et al. Anti-angiogenic effect of tetraacetyl-phytosphingosine. Exp Dermatol. 2007 Apr;16 (4) :311-7. |[2]H J Kim, et al. Potentiation of UVB-induced apoptosis by novel phytosphingosine derivative, tetraacetyl phytosphingosine in HaCaT cell and mouse skin. Apoptosis. 2004 Jul;9 (4) :449-56.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040460-100 1x 100 µL
CD44 Standard (156-3C11), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400003-100 1x 100 µL
CD45RO (UCHL-1), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680460-100 1x 100 µL
CD44 Standard (156-3C11), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details