XL177B
XL177B is an inactive (R) enantiomer of XL177A. XL177B has no effect on CD86 or HLA-DR expression on pDCs. XL177B serves as a negative control. XL177B can be used in the research of multiple myeloma[1].
Product Specifications
CAS Number
2417089-75-7
Product Name Alternative
(R) -XL177A
UNSPSC
12352005
Target
Drug Isomer
Related Pathways
Others
Field of Research
Cancer
Purity
99.36
Smiles
O=C(NCCC[C@@H](C(N1CCC(O)(CC1)CN2C=NC3=C(C2=O)C=CC(NC(CCN4CCN(CC4)C)=O)=C3)=O)CC5=CC=CC=C5)C6=CC7=NC8=C(CCCC8)C(Cl)=C7C=C6
Molecular Formula
C48H57ClN8O5
Molecular Weight
861.47
References & Citations
[1]Ray A, et al. Blockade of deubiquitylating enzyme USP7 in plasmacytoid dendritic cells stimulates anti-myeloma immunity. Blood, 2020, 136: 43.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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