ST4070
ST4070 is a potent, orally active, and selective reversible fatty acid amide hydrolase (FAAH) inhibitor. ST4070 increases endocannabinoid (eCB) brain levels and counteracts neuropathic pain in animal models. ST4070 enhances the endogenous eCB tone in specific brain regions engaged in emotional control, and induces remarkable anxiolytic-like behaviours in rodents. ST4070 can be used for neuropathic pain and anxiety disorders research[1][2].
Product Specifications
CAS Number
1186236-75-8
UNSPSC
12352005
Target
FAAH
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(N1CCCCC1)OC(C2=CC=C(C3=CC=CC=C3)C=C2)=C
Molecular Formula
C20H21NO2
Molecular Weight
307.39
References & Citations
[1]Costanzo MJ, et al. Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives. Bioorg Med Chem Lett. 2008 Mar 15;18 (6) :2114-21.|[2]Marco EM, et al. Potential Therapeutic Value of a Novel FAAH Inhibitor for the Treatment of Anxiety. PLoS One. 2015 Sep 11;10 (9) :e0137034.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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