Nirmatrelvir-d6
Nirmatrelvir-d6 (PF-07321332-d6) is deuterium labeled Nirmatrelvir. Nirmatrelvir (PF-07321332) is a potent and orally active SARS-CoV 3C-like protease (3CLPRO) inhibitor. Nirmatrelvir (PF-07321332) targets to the SARS-CoV-2 virus and can be used for COVID-19 research[1].
Product Specifications
CAS Number
2861202-75-5
Product Name Alternative
PF-07321332-d6
UNSPSC
12352005
Target
Isotope-Labeled Compounds; SARS-CoV
Related Pathways
Anti-infection; Others
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Smiles
O=C(NCC1)[C@@H]1C[C@@H](C#N)NC([C@@H]2[C@]3([H])[C@@](CN2C([C@H](C(C)(C)C)NC(C(F)(F)F)=O)=O)([H])C3(C([2H])([2H])[2H])C([2H])([2H])[2H])=O
Molecular Formula
C23H26D6F3N5O4
Molecular Weight
505.56
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]KoenVandyck, et al. Considerations for the Discovery and Development of 3-Chymotrypsin-Like Cysteine Protease Inhibitors Targeting SARS-CoV-2 Infection. Current Opinion in Virology Available online 27 April 2021
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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