Tetrahydropteroylpentaglutamate

Tetrahydropteroylpentaglutamate (H4PteGlu5) is an inhibitor for 10-CHO-THF dehydrogenase with a Kd of 20 nM through binding of an irreversible o 10-CHO-THF dehydrogenase-H4PteGlu5 complex[1].

Product Specifications

CAS Number

[41520-73-4]

Product Name Alternative

H4PteGlu5

UNSPSC

12352005

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Smiles

O=C1C2=C(NC(N)=N1)NCC(N2)CNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)=O)=O

Molecular Formula

C39H51N11O18

Molecular Weight

961.89

References & Citations

[1]Kim DW, et al., Properties of tetrahydropteroylpentaglutamate bound to 10-formyltetrahydrofolate dehydrogenase. Biochemistry. 1996 Dec 10;35 (49) :15772-83.