Tetrahydropteroylpentaglutamate
Tetrahydropteroylpentaglutamate (H4PteGlu5) is an inhibitor for 10-CHO-THF dehydrogenase with a Kd of 20 nM through binding of an irreversible o 10-CHO-THF dehydrogenase-H4PteGlu5 complex[1].
Product Specifications
CAS Number
41520-73-4
Product Name Alternative
H4PteGlu5
UNSPSC
12352005
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Smiles
O=C1C2=C(NC(N)=N1)NCC(N2)CNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)=O)=O
Molecular Formula
C39H51N11O18
Molecular Weight
961.89
References & Citations
[1]Kim DW, et al., Properties of tetrahydropteroylpentaglutamate bound to 10-formyltetrahydrofolate dehydrogenase. Biochemistry. 1996 Dec 10;35 (49) :15772-83.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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