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7-Hydroxyrisperidone

7-Hydroxyrisperidone (7-RispOH) is a metabolite of Risperidone. Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist[1][2].

Product Specifications

CAS Number

147663-04-5

Product Name Alternative

7-RispOH

UNSPSC

12352005

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Smiles

O=C1C(CCN2CCC(CC2)C3=NOC4=C3C=CC(F)=C4)=C(C)N=C5N1CC(CC5)O

Molecular Formula

C23H27FN4O3

Molecular Weight

426.48

References & Citations

[1]Liana I de Jesus, et al. Enantioselective fungal biotransformation of risperidone in liquid culture medium by capillary electrophoresis and hollow fiber liquid-phase microextraction. Electrophoresis. 2011 Oct;32 (19) :2765-75. |[2]Nyberg S, et al. 5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone. Psychopharmacology (Berl) . 1993;110 (3) :265-72.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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