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BLX-3887

BLX-3887 is a selective 15-lipoxygenase type 1 (15-LO-1) inhibitor with an IC50 of 32 nM. BLX-3887 can be utilized in research related to the 15-LO pathways[1].

Product Specifications

CAS Number

934758-70-0

UNSPSC

12352005

Target

Lipoxygenase

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Smiles

O=C(C1=NNC(Cl)=C1Cl)NC2=CC=C(F)C=C2Cl

Molecular Formula

C10H5Cl3FN3O

Molecular Weight

308.52

References & Citations

[1]Archambault AS, et al. Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils. PLoS One. 2018 Aug 17;13 (8) :e0202424.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

15-LOX

Available Sizes

Frequently Asked Questions

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