Blebbistatin (Standard)

Blebbistatin (Standard) is the analytical standard of Blebbistatin. This product is intended for research and analytical applications. Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function. Blebbistatin blocks cell migration[1][2].

Product Specifications

CAS Number

[674289-55-5]

UNSPSC

12352100

Target

Myosin; Reference Standards

Related Pathways

Cytoskeleton; Others

Field of Research

Others

Smiles

O=C1C2(O)C(N(C3=CC=CC=C3)CC2)=NC4=C1C=C(C)C=C4

Molecular Formula

C18H16N2O2

Molecular Weight

292.34

References & Citations

[1]Ho WT, et al. Targeting non-muscle myosin II promotes corneal endothelial migration through regulating lamellipodial dynamics. J Mol Med (Berl) . 2019 Sep;97 (9) :1345-1357.|[2]Liang Ma, et al. Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration. Cell Res. 2015 Jan;25 (1) :24-38.