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Salvinorin A propionate

Salvinorin A (Divinorin A) propionate is a potent, unique and short-acting high efficacy kappa-opioid receptor (KOPr) agonist with Ki value of 4.3 nm. Salvinorin A propionate is a non-nitrogenous neoclerodane isolated from Salvia divinorum[1].

Product Specifications

CAS Number

689295-71-4

UNSPSC

12352005

Target

Opioid Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Cardiovascular Disease

Smiles

C[C@@]([C@@]1([H])CC2)(C[C@@H](C3=COC=C3)OC1=O)[C@](C([C@H]4OC(CC)=O)=O)([H])[C@@]2([C@@H](C4)C(OC)=O)C

Molecular Formula

C24H30O8

Molecular Weight

446.49

References & Citations

[1]Butelman ER, et al. Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders. Front Pharmacol. 2015 Sep 8; 6:190., et al. |[2]John TF, et al. The antinociceptive effect of salvinorin A in mice.Eur J Pharmacol. 2006 Sep 18;545 (2-3) :129-33. Epub 2006 Jul 4.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

κ Opioid Receptor/KOR

Available Sizes

Frequently Asked Questions

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