Motolimod (Standard)
Motolimod (Standard) is the analytical standard of Motolimod. This product is intended for research and analytical applications. Motolimod (VTX-2337; VTX-378) is a selective Toll-like receptor 8 (TLR8) agonist, with an EC50 of approximately 100 nM.
Product Specifications
CAS Number
926927-61-9
UNSPSC
12352100
Target
Reference Standards; Toll-like Receptor (TLR)
Related Pathways
Immunology/Inflammation; Others
Field of Research
Cancer
Smiles
O=C(C1=CC2=CC=C(C3=CC=C(C(N4CCCC4)=O)C=C3)C=C2N=C(N)C1)N(CCC)CCC
Molecular Formula
C28H34N4O2
Molecular Weight
458.60
References & Citations
[1]Lu H, et al. VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC. Clin Cancer Res. 2012 Jan 15;18 (2) :499-509.|[2]Dietsch GN, et al. Coordinated Activation of Toll-Like Receptor8 (TLR8) and NLRP3 by the TLR8 Agonist, VTX-2337, Ignites Tumoricidal Natural Killer Cell Activity. PLoS One. 2016 Feb 29;11 (2) :e0148764.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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