GMPCP (trisodium)
GMPCP (GpCp) trisodium (Compound 7 trisodium) is a guanosine derivative is a CD73 inhibitor, with Kis of 1110 nM (rat soluble CD73) and 410 nM (human soluble CD73) respectively. GMPCP (GpCp) trisodium can be used for research of cancer[1].
Product Specifications
Product Name Alternative
GpCp (trisodium)
UNSPSC
12352005
Target
CD73
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2NC(N)=NC3=O)O[C@@H]1COP(CP(O[Na])(O[Na])=O)(O[Na])=O
Molecular Formula
C11H14N5Na3O10P2
Molecular Weight
507.17
References & Citations
[1]Bhattarai S, et al. 2-Substituted α, β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes. J Med Chem. 2020 Mar 26;63 (6) :2941-2957.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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