PET-cGMP
PET-cGMP is a cyclic guanosine monophosphate analog and an effective selective agonist of PKG I, the EC50 of PET-cGMP for PKG Iβ is 3.8 nM, while for PKG II, it's 193 nM[1].
Product Specifications
CAS Number
78080-27-0
UNSPSC
12352005
Target
PKG
Related Pathways
Stem Cell/Wnt
Field of Research
Cardiovascular Disease
Smiles
O=C1C2=C(NC3=NC(C4=CC=CC=C4)=CN13)N([C@]5([H])O[C@@](CO[P]6(O)=O)([H])[C@](O6)([H])[C@H]5O)C=N2
Molecular Formula
C18H16N5O7P
Molecular Weight
445.32
References & Citations
[1]James C Campbell, et al. Structural Basis of Analog Specificity in PKG I and II. ACS Chem Biol. 2017 Sep 15;12 (9) :2388-2398.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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