5'-Phosphoguanylyl- (3',5') -guanosine (trisodium)
5'-Phosphoguanylyl- (3',5') -guanosine trisodium (pGpG trisodium) is an intermediate molecule produced by the pathway for enzymatic cyclic diguanylate (c-di-GMP) degradation. 5'-Phosphoguanylyl- (3',5') -guanosine trisodium can be used to detect the metabolism of nucleic acids[1][2].
Product Specifications
Product Name Alternative
PGpG (trisodium)
UNSPSC
12352005
Target
STING
Related Pathways
Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=C1C2=C(N([C@H]3[C@H](O)[C@H](O)[C@@H](COP(O[C@H]4[C@@H](O)[C@H](N(C=N5)C6=C5C(N=C(N)N6)=O)O[C@@H]4COP(O[Na])(O[Na])=O)(O[Na])=O)O3)C=N2)NC(N)=N1
Molecular Formula
C20H23N10Na3O15P2
Molecular Weight
774.37
References & Citations
[1]Nesbitt NM, et, al. Modification of a bi-functional diguanylate cyclase-phosphodiesterase to efficiently produce cyclic diguanylate monophosphate. Biotechnol Rep (Amst) . 2015 May 5;7:30-37. |[2]Cohen D, et, al. Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2015 Sep 8;112 (36) :11359-64.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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