Purine riboside-5'-O-triphosphate (sodium)
Purine riboside-5'-O-triphosphate sodium, an active metabolite of Nebularine (HY-103694), acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 µM and 28 µM for the human enzyme, respectively. Purine riboside-5'-O-triphosphate sodium inhibits calmodulin-dependent protein kinase II (CaMKII) with a Ki value of 590 µM[1][2][3].
Product Specifications
CAS Number
[35892-95-6]
Product Name Alternative
PTP (tetrasodium)
UNSPSC
12352005
Target
CaMK; DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/DNA Damage; Neuronal Signaling
Field of Research
Metabolic Disease
Smiles
O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O)N2C3=NC=NC=C3N=C2
Molecular Formula
C10H11N4Na4O13P3
Molecular Weight
580.09
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-137658A/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Rabbit anti-Saccharomyces cerevisiae (strain Lalvin EC1118/Prise de mousse)(Baker's yeast) TDA2 Polyclonal Antibody
