Rp-dUTPαS (tetrasodium)
Rp-dUTPαS (tetrasodium) is an isomer of the sulfur-containing nucleoride dUTP-α-S and an agonist of the purinergic P2Y2 receptor. Rp-dUTPαS (tetrasodium) selectively induces inositol phosphate accumulation in P2Y2-expressing 1321N1 cells with an EC50 of 12.5 μM[1].
Product Specifications
UNSPSC
12352005
Target
P2Y Receptor
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=[P@](OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(OC[C@@H]1[C@@H](O)C[C@H](N2C=CC(NC2=O)=O)O1)S[Na]
Molecular Formula
C9H11N2Na4O13P3S
Molecular Weight
572.13
References & Citations
[1]Jacobson, K. A., et al., (2006) . Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5'-triphosphate analogues at the human P2Y2 and P2Y4 receptors. Biochemical pharmacology, 71 (4), 540–549.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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