Rp-UTP-α-S (tetrasodium)

Rp-UTP-α-S (Rp-Uridine 5'-O- (1-thiotriphosphate) ) tetrasodium is a nucleotide agonist of purinergic P2Y2 and P2Y4 receptors. Rp-UTP-α-S (tetrasodium) can induce inositol phosphate accumulation in P2Y2 or P2Y4 expressing 1321N1 cells with EC50 values of 5.4 and 27 μM[1].

Product Specifications

Product Name Alternative

Rp-Uridine 5'-O- (1-thiotriphosphate) (tetrasodium)

UNSPSC

12352005

Target

P2Y Receptor

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O[C@H]1[C@@H](O)[C@H](N2C=CC(NC2=O)=O)O[C@@H]1CO[P@](OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(S[Na])=O

Molecular Formula

C9H11N2Na4O14P3S

Molecular Weight

588.13

References & Citations

[1]Jacobson, K. A., et al., (2006) . Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5'-triphosphate analogues at the human P2Y2 and P2Y4 receptors. Biochemical pharmacology, 71 (4), 540–549.