Uridine 5'-O-thiodiphosphate (trisodium)
Uridine 5'-O-thiodiphosphate (trisodium) (UDP-β-S (trisodium) ) is a purinergic P2Y6 receptor agonist. Uridine 5'-O-thiodiphosphate (trisodium) selectively induces accumulation of inositol phosphates in 1321N1 cells expressing P2Y6 receptors (EC50 = 28 nM) . Uridine 5'-O-thiodiphosphate (trisodium) induces DNA synthesis in rat aortic smooth muscle cells[1].
Product Specifications
Product Name Alternative
UDP-β-S (trisodium)
UNSPSC
12352005
Target
DNA/RNA Synthesis; P2Y Receptor
Related Pathways
Cell Cycle/DNA Damage; GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O[C@H]1[C@@H](O)[C@H](N2C=CC(NC2=O)=O)O[C@@H]1COP(OP(O[Na])(S[Na])=O)(O[Na])=O
Molecular Formula
C9H11N2Na3O11P2S
Molecular Weight
486.17
References & Citations
[1]Hou M, et al. UDP acts as a growth factor for vascular smooth muscle cells by activation of P2Y (6) receptors. Am J Physiol Heart Circ Physiol. 2002 Feb;282 (2) :H784-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2Y6 Receptor
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
