Leucyl-phenylalanine amide

Leucyl-phenylalanine amide (L-Leucyl-L-phenylalaninamide) is a dipeptide analog. Leucyl-phenylalanine amide is a ligand of SP1-7 with a Ki value of 10.2 nM. Leucyl-phenylalanine amide shows no binding activity to human NK-1 or NK-3 receptors[1].

Product Specifications

CAS Number

[38678-60-3]

Product Name Alternative

L-Leucyl-L-phenylalaninamide

UNSPSC

12352005

Target

Neurokinin Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

NC([C@@H](NC([C@@H](N)CC(C)C)=O)CC1=CC=CC=C1)=O

Molecular Formula

C15H23N3O2

Molecular Weight

277.36

References & Citations

[1]Fransson R, et al. Discovery of dipeptides with high affinity to the specific binding site for substance P1-7. J Med Chem. 2010 Mar 25;53 (6) :2383-9.