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Asundexian-d3

Asundexian-d3 (BAY-2433334-d3) is the deuterium labeled Asundexian (HY-137431) . Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM[1].

Product Specifications

CAS Number

[2975248-62-3]

Product Name Alternative

BAY-2433334-d3

UNSPSC

12352005

Target

Factor Xa; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cardiovascular Disease

Smiles

ClC1=CC(C(C(OC([2H])([2H])[2H])=CN2[C@@H](CC)C(NC3=CC(F)=C(C=C3)C(N)=O)=O)=CC2=O)=C(N4C=C(N=N4)C(F)(F)F)C=C1

Molecular Formula

C26H18D3ClF4N6O4

Molecular Weight

595.95

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Curated Selection

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