Asundexian-d3
Asundexian-d3 (BAY-2433334-d3) is the deuterium labeled Asundexian (HY-137431) . Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM[1].
Product Specifications
CAS Number
[2975248-62-3]
Product Name Alternative
BAY-2433334-d3
UNSPSC
12352005
Target
Factor Xa; Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease
Smiles
ClC1=CC(C(C(OC([2H])([2H])[2H])=CN2[C@@H](CC)C(NC3=CC(F)=C(C=C3)C(N)=O)=O)=CC2=O)=C(N4C=C(N=N4)C(F)(F)F)C=C1
Molecular Formula
C26H18D3ClF4N6O4
Molecular Weight
595.95
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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