Quinacrine (hydrochloride hydrate) (Standard)

Quinacrine (hydrochloride hydrate) (Standard) is the analytical standard of Quinacrine (hydrochloride hydrate) . This product is intended for research and analytical applications. Quinacrine hydrochloride hydrate (Mepacrine hydrochloride hydrate) is an antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine hydrochloride hydrate suppresses NF-κB and activates p53 signaling, which results in the induction of the apoptosis[1].

Product Specifications

CAS Number

[6151-30-0]

UNSPSC

12352100

Target

Apoptosis; Autophagy; Mitophagy; Parasite; Reference Standards

Related Pathways

Anti-infection; Apoptosis; Autophagy; Others

Field of Research

Cancer; Infection

Smiles

CC(NC1=C(C=C(OC)C=C2)C2=NC3=CC(Cl)=CC=C31)CCCN(CC)CC.[H]Cl.[H]Cl.[H]O[H].[H]O[H]

Molecular Formula

C23H36Cl3N3O3

Molecular Weight

508.91

References & Citations

[1]Xiaoyang Wu, et al. Quinacrine Inhibits Cell Growth and Induces Apoptosis in Human Gastric Cancer Cell Line SGC-7901. Curr Ther Res Clin Exp. 2012 Feb;73 (1-2) :52-64.|[2]Anna Eriksson, et al. Towards repositioning of quinacrine for treatment of acute myeloid leukemia - Promising synergies and in vivo effects. Leuk Res. 2017 Dec;63:41-46.