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N-Methylspiroperidol

N-Methylspiroperidol is a D2 receptor antagonist. N-Methylspiroperidol can be labeled as [18F]N-Methylspiroperidol and used in PET (Positron Emission Tomography) to study how it binds to the 5-HT2C receptor and the competition and effects of neurotransmitters like dopamine on these receptors[1].

Product Specifications

CAS Number

87539-19-3

UNSPSC

12352005

Target

Dopamine Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C(CCCN1CCC2(CC1)C(N(CN2C3=CC=CC=C3)C)=O)C4=CC=C(C=C4)F

Molecular Formula

C24H28FN3O2

Molecular Weight

409.50

References & Citations

[1]Logan J, et al. Effects of endogenous dopamine on measures of [18F]N-methylspiroperidol binding in the basal ganglia: comparison of simulations and experimental results from PET studies in baboons. Synapse. 1991 Nov;9 (3) :195-207.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT2 Receptor; D2 Receptor

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