N-Methylspiroperidol
N-Methylspiroperidol is a D2 receptor antagonist. N-Methylspiroperidol can be labeled as [18F]N-Methylspiroperidol and used in PET (Positron Emission Tomography) to study how it binds to the 5-HT2C receptor and the competition and effects of neurotransmitters like dopamine on these receptors[1].
Product Specifications
CAS Number
[87539-19-3]
UNSPSC
12352005
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(CCCN1CCC2(CC1)C(N(CN2C3=CC=CC=C3)C)=O)C4=CC=C(C=C4)F
Molecular Formula
C24H28FN3O2
Molecular Weight
409.50
References & Citations
[1]Logan J, et al. Effects of endogenous dopamine on measures of [18F]N-methylspiroperidol binding in the basal ganglia: comparison of simulations and experimental results from PET studies in baboons. Synapse. 1991 Nov;9 (3) :195-207.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor; D2 Receptor
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