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Carbuterol (hydrochloride)

Carbuterol (SKF 40383-A) hydrochloride is a selective β2-adrenergic receptor agonist that primarily targets bronchial smooth muscle, exhibiting significant bronchodilatory and anti-allergic activity. Carbuterol hydrochloride can directly inhibit the immunologically induced release of histamine and slow-reacting substance of anaphylaxis (SRS-A), thereby alleviating allergic responses. In addition, it exerts mild β1-mediated cardiac stimulation and is applicable to studies related to respiratory and immune-related diseases such as asthma and allergic disorders[1].

Product Specifications

CAS Number

34866-46-1

Product Name Alternative

SKF 40383-A (hydrochloride)

UNSPSC

12352005

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Inflammation/Immunology

Smiles

O=C(NC1=CC(C(CNC(C)(C)C)O)=CC=C1O)N.Cl

Molecular Formula

C13H22ClN3O3

Molecular Weight

303.79

References & Citations

[1]Colella DF, et al. Characterization of the adrenergic activity of carbuterol (SK&F 40383-A) . Eur J Pharmacol. 1977 Dec 1;46 (3) :229-41.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

β adrenergic receptor

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