Carbuterol (hydrochloride)
Carbuterol (SKF 40383-A) hydrochloride is a selective β2-adrenergic receptor agonist that primarily targets bronchial smooth muscle, exhibiting significant bronchodilatory and anti-allergic activity. Carbuterol hydrochloride can directly inhibit the immunologically induced release of histamine and slow-reacting substance of anaphylaxis (SRS-A), thereby alleviating allergic responses. In addition, it exerts mild β1-mediated cardiac stimulation and is applicable to studies related to respiratory and immune-related diseases such as asthma and allergic disorders[1].
Product Specifications
CAS Number
[34866-46-1]
Product Name Alternative
SKF 40383-A (hydrochloride)
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Inflammation/Immunology
Smiles
O=C(NC1=CC(C(CNC(C)(C)C)O)=CC=C1O)N.Cl
Molecular Formula
C13H22ClN3O3
Molecular Weight
303.79
References & Citations
[1]Colella DF, et al. Characterization of the adrenergic activity of carbuterol (SK&F 40383-A) . Eur J Pharmacol. 1977 Dec 1;46 (3) :229-41.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor
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