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(R) -N-3-Benzylnirvanol

(R) -N-3-Benzylnirvanol is the R-isomer of (±) -N-3-Benzylnirvanol. (±) -N-3-Benzylnirvanol is a racemic mixture of (+) -N-3-Benzylnirvanol and (-) -N-3-Benzylnirvanol. (+) -N-3-Benzylnirvanol and (–) -N-3-Benzylnirvanol are potent and selective cytochrome P450 inhibitors with Ki values of 0.25 and 5.3 μM for CYP2C19, respectively[1].

Product Specifications

CAS Number

790676-41-4

UNSPSC

12352005

Hazard Statement

H302-H319-H372-H410

Target

Cytochrome P450; Drug Isomer

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Smiles

C(C)[C@]1(C(=O)N(CC2=CC=CC=C2)C(=O)N1)C3=CC=CC=C3

Molecular Formula

C18H18N2O2

Molecular Weight

294.35

Precautions

P260-P264-P270-P273-P280-P305+P351+P338-P330-P391-P501

References & Citations

[1]Hisashi Suzuki, et al. (+) -N-3-Benzyl-nirvanol and (-) -N-3-benzyl-phenobarbital: new potent and selective in vitro inhibitors of CYP2C19. Drug Metab Dispos. 2002 Mar;30 (3) :235-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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