(R) -N-3-Benzylnirvanol
(R) -N-3-Benzylnirvanol is the R-isomer of (±) -N-3-Benzylnirvanol. (±) -N-3-Benzylnirvanol is a racemic mixture of (+) -N-3-Benzylnirvanol and (-) -N-3-Benzylnirvanol. (+) -N-3-Benzylnirvanol and (–) -N-3-Benzylnirvanol are potent and selective cytochrome P450 inhibitors with Ki values of 0.25 and 5.3 μM for CYP2C19, respectively[1].
Product Specifications
CAS Number
790676-41-4
UNSPSC
12352005
Hazard Statement
H302-H319-H372-H410
Target
Cytochrome P450; Drug Isomer
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
C(C)[C@]1(C(=O)N(CC2=CC=CC=C2)C(=O)N1)C3=CC=CC=C3
Molecular Formula
C18H18N2O2
Molecular Weight
294.35
Precautions
P260-P264-P270-P273-P280-P305+P351+P338-P330-P391-P501
References & Citations
[1]Hisashi Suzuki, et al. (+) -N-3-Benzyl-nirvanol and (-) -N-3-benzyl-phenobarbital: new potent and selective in vitro inhibitors of CYP2C19. Drug Metab Dispos. 2002 Mar;30 (3) :235-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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