16-Phenoxy tetranor Prostaglandin E2

16-phenoxy tetranor PGE2 is the free acid form of sulprostone formed by the hydrolysis of the methylsulfonamide bond.1 16-phenoxy tetranor PGE2 is a minor metabolite of sulprostone found in human plasma after parenteral administration of the drug.

Product Specifications

CAS Number

[54382-74-0]

Product Name Alternative

16-Phenoxy tetranor PGE2

UNSPSC

12352005

Hazard Statement

H225-H319-H336-H360

Target

Prostaglandin Receptor

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

OC(CCC/C=C\C[C@@H](C(C1)=O)[C@H]([C@@H]1O)/C=C/[C@@H](O)COC2=CC=CC=C2)=O

Molecular Formula

C22H28O6

Molecular Weight

388.45

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Kuhnz, et al. Identification of the major metabolites of the prostaglandin E2-analogue sulprostone in human plasma, and isolation from urine (in vivo) and liver perfusate (in vitro) of female guinea-pigs. Drug Metab. Dispos. 19 (5), 920-925 (1991) .