BP 2-94

BP 2-94 (BP 2.94) is an orally active and highly selective prodrug targeting the histamine H3 receptor. BP 2-94 exerts anti-inflammatory, analgesic and antinociceptive effects by inhibiting histamine release and modulating neurogenic inflammation. BP 2-94 is promising for research of asthma, migraines, and inflammatory pain-related disorders[1].

Product Specifications

CAS Number

139191-80-3

Product Name Alternative

BP 2.94

UNSPSC

12352005

Target

Histamine Receptor

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

OC1=C(C=CC=C1)/C(C2=CC=CC=C2)=N\[C@@H](CC3=CN=CN3)C

Molecular Formula

C19H19N3O

Molecular Weight

305.37

References & Citations

[1]Rouleau A, et al. Bioavailability, antinociceptive and antiinflammatory properties of BP 2-94, a histamine H3 receptor agonist prodrug. J Pharmacol Exp Ther. 1997 Jun;281 (3) :1085-94.