Lycorine methiodide

Lycorine methiodide (N-Methyllycorine iodide) is a derivative of Lycorine (HY-N0288) . Lycorine methiodide exhibits no significant in vitro antitumor activity against A549, OE21, Hs683, U373, SKMEL, and B16F10 cell lines, with all IC50 values greater than 10 μM[1].

Product Specifications

CAS Number

[15069-99-5]

Product Name Alternative

N-Methyllycorine (iodide)

UNSPSC

12352005

Target

Drug Derivative

Related Pathways

Others

Field of Research

Cancer

Smiles

C[N+]12[C@@]3([H])[C@]([C@@H]([C@H](C=C3CC2)O)O)([H])C4=CC(OCO5)=C5C=C4C1.[I-]

Molecular Formula

C17H20INO4

Molecular Weight

429.25

References & Citations

[1]Lamoral-Theys D, et al. Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight. J Med Chem. 2009 Oct 22;52 (20) :6244-56.