Mergocriptine

Mergocriptine (CBM36-733) is a dopamine receptor agonist and SARS-CoV-2 Mpro ligand. Mergocriptine regulates ambulatory activity[1][2].

Product Specifications

CAS Number

[81968-16-3]

Product Name Alternative

CBM36-733

UNSPSC

12352005

Target

Dopamine Receptor; SARS-CoV; Virus Protease

Related Pathways

Anti-infection; GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-anti-virus

Field of Research

Infection; Neurological Disease

Smiles

O[C@@]([C@@](CCC1)([H])N1C2=O)(O[C@](C(C)C)3NC([C@@H](CN4C)C=C([C@@]4([H])C5)C6=CC=CC(N7)=C6C5=C7C)=O)N([C@H]2CC(C)C)C3=O

Molecular Formula

C33H43N5O5

Molecular Weight

589.73

References & Citations

[1]Piplani S, et al. Computational Repurposing of Drugs and Natural Products Against SARS-CoV-2 Main Protease (Mpro) as Potential COVID-19 Therapies. Front Mol Biosci. 2022 Mar 14;9:781039.|[2]Kuribara H, et al. Behavioral study on mergocriptine (CBM36-733) by ambulatory activity in mice: repeated administration and interaction with methamphetamine. Jpn J Pharmacol. 1990 Oct;54 (2) :163-70.