Mergocriptine
Mergocriptine (CBM36-733) is a dopamine receptor agonist and SARS-CoV-2 Mpro ligand. Mergocriptine regulates ambulatory activity[1][2].
Product Specifications
CAS Number
[81968-16-3]
Product Name Alternative
CBM36-733
UNSPSC
12352005
Target
Dopamine Receptor; SARS-CoV; Virus Protease
Related Pathways
Anti-infection; GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-anti-virus
Field of Research
Infection; Neurological Disease
Smiles
O[C@@]([C@@](CCC1)([H])N1C2=O)(O[C@](C(C)C)3NC([C@@H](CN4C)C=C([C@@]4([H])C5)C6=CC=CC(N7)=C6C5=C7C)=O)N([C@H]2CC(C)C)C3=O
Molecular Formula
C33H43N5O5
Molecular Weight
589.73
References & Citations
[1]Piplani S, et al. Computational Repurposing of Drugs and Natural Products Against SARS-CoV-2 Main Protease (Mpro) as Potential COVID-19 Therapies. Front Mol Biosci. 2022 Mar 14;9:781039.|[2]Kuribara H, et al. Behavioral study on mergocriptine (CBM36-733) by ambulatory activity in mice: repeated administration and interaction with methamphetamine. Jpn J Pharmacol. 1990 Oct;54 (2) :163-70.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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