(Rac) -UCB-J

(Rac) -UCB-J (Compound 23) is a ligand for synaptic vesicle protein 2A (SV2A), with a pIC50 value of 8.2. (Rac) -UCB-J can be used as a PET tracer for SV2A to assist in the diagnosis of epilepsy research[1].

Product Specifications

CAS Number

[1604786-87-9]

UNSPSC

12352005

Target

Synaptic Vesicle Proteins

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C1CC(C2=CC(F)=C(C(F)=C2)F)CN1CC3=CC=NC=C3C

Molecular Formula

C17H15F3N2O

Molecular Weight

320.31

References & Citations

[1]Joël Mercier, et al. Discovery of heterocyclic nonacetamide synaptic vesicle protein 2A (SV2A) ligands with single-digit nanomolar potency: opening avenues towards the first SV2A positron emission tomography (PET) ligands. ChemMedChem. 2014 Apr;9 (4) :693-8.