Meisoindigo (Standard)
Meisoindigo (Standard) is the analytical standard of Meisoindigo. This product is intended for research and analytical applications. Meisoindigo (Dian III), a derivative of Indirubin , halts the cell cycle at the G0/G1 phase and induces apoptosis in primary acute myeloid leukemia (AML) cells. Meisoindigo exhibits high antitumor activity[1][2].
Product Specifications
CAS Number
97207-47-1
UNSPSC
12352100
Target
Apoptosis; Reference Standards
Related Pathways
Apoptosis; Others
Field of Research
Cancer
Smiles
O=C1N(C)C2=C(C=CC=C2)/C1=C3C(NC4=C\3C=CC=C4)=O
Molecular Formula
C17H12N2O2
Molecular Weight
276.29
References & Citations
[1]Lee CC, et al. Meisoindigo is a promising agent with in vitro and in vivo activity against human acute myeloid leukemia. Leuk Lymphoma. 2010 May;51 (5) :897-905.|[2]Yingze Ye, et al. Meisoindigo Protects Against Focal Cerebral Ischemia-Reperfusion Injury by Inhibiting NLRP3 Inflammasome Activation and Regulating Microglia/Macrophage Polarization via TLR4/NF-κB Signaling Pathway. Front Cell Neurosci. 2019 Dec 16;13:553.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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