YJC-10592
YJC-10592 is an orally active CCR-2 antagonist. YJC-10592 binds to HAS. YJC-10592 can be used in the research of asthma and idiopathic dermatitis[1].
Product Specifications
CAS Number
[1226894-87-6]
UNSPSC
12352005
Target
CCR
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
O=C(NCC(N[C@H]1CN(CCN2CCN(C(C3=CC=CC=C3Cl)=O)CC2)CC1)=O)C4=CC=CC(C(F)(F)F)=C4
Molecular Formula
C27H31ClF3N5O3
Molecular Weight
566.01
References & Citations
[1]Du ES, et al. Pharmacokinetics of YJC-10592, a novel chemokine receptor 2 (CCR-2) antagonist, in rats. Arch Pharm Res. 2016 Jun;39 (6) :833-42.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CCR2
Curated Selection
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