(R) -Xanthoanthrafil
(R) -Xanthoanthrafil is a phosphodiesterase-5 (PDE5) inhibitor. (R) -Xanthoanthrafil selectively inhibits PDE5, increasing cyclic guanosine monophosphate (cGMP) levels, leading to smooth muscle relaxation and promoting penile erection. (R) -Xanthoanthrafil can be used to study erectile dysfunction[1].
Product Specifications
CAS Number
[247568-68-9]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=C(NCC1=CC=C(OC)C(OC)=C1)C2=CC([N+]([O-])=O)=CC=C2N[C@H](C)CO
Molecular Formula
C19H23N3O6
Molecular Weight
389.40
References & Citations
[1]Kumasaka K, et al. Determination of (R) -xanthoanthrafil, a phosphodiesterase-5 inhibitor, in a dietary supplement promoted for sexual enhancement. Chem Pharm Bull (Tokyo) . 2008 Feb;56 (2) :227-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE5
Curated Selection
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