3'-Hydroxy simvastatin
3'-Hydroxy simvastatin is a metabolite of simvastatin. Simvastatin is an orally active competitive inhibitor of HMG-CoA reductase (HMGCR) (Ki: 0.2 nM).
Product Specifications
CAS Number
1283861-33-5
UNSPSC
12352005
Target
Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Smiles
[H][C@@]1([C@H](C=CC2=C[C@@H](C[C@@H]([C@@]21[H])OC(C(C)(C(O)C)C)=O)C)C)CC[C@@]3([H])OC(C[C@@H](C3)O)=O
Molecular Formula
C25H38O6
Molecular Weight
434.57
References & Citations
[1]Slater EE, et al. Mechanism of action and biological profile of HMG CoA reductase inhibitors. A new therapeutic alternative. Drugs. 1988;36 Suppl 3:72-82.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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